HOW RESPONSE DESIGNS AND CLASS PROPORTIONS AFFECT THE ACCURACY OF VALIDATION DATA



Case report: Regression of Glioblastoma after flavivirus infection

Glioblastoma is the most frequent and aggressive ut solution gel for cats primary brain cancer.In preclinical studies, Zika virus, a flavivirus that triggers the death of glioblastoma stem-like cells.However, the flavivirus oncolytic activity has not been demonstrated in human patients.Here we report a glioblastoma patient who received the standard

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Immunosuppressive tumor-associated macrophages expressing interlukin-10 conferred poor prognosis and therapeutic vulnerability in patients with muscle-invasive bladder cancer

Background Tumor-associated macrophages (TAMs) secreting IL-10 could be a specific functional cell subset with distinct polarization state and suppressive role in antitumor immune response.Here, we assessed the associations of clinical outcome, therapeutic responses and molecular features with IL-10+TAMs infiltration, and potential impact of IL-10+

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